G5 Reproducibility in Clinical Research

Coordinator
Prof.dr. Lenny Verkooijen

Contact
Prof.dr. Lenny Verkooijen

Organisation
The course is a joint initiative of the Graduate Programme Medical Imaging ImagO and the MSc Epidemiology 

Date
28 April – 1 May 2020  
Register
by sending an email to ImagO

Location
University Medical Center Utrecht

Description
Over the past decades, we have seen huge improvements in medical imaging technology. Systematic evaluation of the quality and reproducibility of new imaging techniques is crucial to allow large scale implementation. The course is targeted at PhD candidates involved in diagnostic research/clinical imaging research, clinical physicists with clinical focus, epidemiologists/statisticians involved in clinical imaging research.

Course content
This one week interactive course will focus on the many aspects of imaging evaluation, including technical development, visual assessment and optimisation of image quality, and intra and inter observer reproducibility.
At the end of the week, the student will be able to design, analyse and report imaging evaluation and reproducibility studies according to international guidelines.

Course objectives
● Explain the principles of the various imaging modalities (e.g. CT, MRI)
● Apply different methods for evaluation of image quality
● Explain the concepts of intra- and interobserver reliability and reproducability
● Design studies aimed at evaluating intra- and interobserver reliability and agreement
● Apply statistical analyses regarding reliability and reproducibility
● Report on reliability and reproducibility according to the GRRAS guidelines

Prerequisites
Basic knowledge on epidemiology and statistics is an advantage

Literature

Examination
80% attendance and exam